MOL 440 (STN)
Genome Integrity and Human Disease
ENROLLMENT BY APPLICATION OR INTERVIEW. DEPARTMENTAL PERMISSION REQUIRED.
Sample reading list:
Greider CW, Blackburn EH. 1985 Cell. 43:405-13., Identification of a specific telomere terminal transferase
activity in Tetrahymena extracts.
Blasco MA, et al. 1997 Cell. 91:25-34., Telomere shortening and tumor formation by mouse cells
lacking telomerase RNA.
Mitchell JR, Wood E, Collins K. 1999 Nature. 402:551-5, A telomerase component is defective in the human disease
See instructor for complete list
Students will read around 20 pages weekly, depending on the degree of difficulty as well as the size and number of illustrations. Students will be expected to write a two page paper that summarizes the paper from the primary literature assigned for that day.
Final Exam - 35%
Papers - 30%
Class/Precept Participation - 35%
Not Open to Freshmen.
Class size is limted to 10. Contact instructor for permission to enroll.
|20925||S01||3:00 pm - 4:20 pm||M W||Thomas Laboratory 117||Enrolled:4 Limit:10|