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Course Details

Fall 2011-2012
CHM 440  

Drug Discovery in the Genomics Era

Paul J. Reider

A detailed review of recent successes and failures in the discovery of new drugs. Therapeutic areas to be discussed include: HIV, oncology, asthma, Alzheimer's Disease, antibiotics, diabetes, and neglected diseases (malaria, TB, human African Trypaonosomiasis). Case studies presented by leading pharmaceutical scientists will complement discussions of the functional steps required to select a target, indentify a new chemical entity, and get it to patients. The course will emphasize the integration of the molecular sciences and the role of chemistry in inventing and producing important new medicines.


Sample reading list:
See instructor for complete list

Reading/Writing assignments:
Readings from the current literature.

Requirements/Grading:
Take Home Mid term Exam - 35%
Take Home Final Exam - 35%
Papers - 15%
Class/Precept Participation - 15%

Other Requirements:
Open to Juniors, Seniors, and Graduate Students Only.

Prerequisites and Restrictions:
Two semesters of organic chemistry (CHM 301 & 302 OR CHM 303 & 304/304B) or the equivalent..

Schedule/Classroom assignment:

Class numberSectionTimeDaysRoomEnrollmentStatus
22319 L01 11:00 am - 12:20 pm M W   Lewis Library   138   Enrolled:47 Limit:75
22320 C01 2:30 pm - 3:20 pm T   McDonnell Hall   106   Enrolled:11 Limit:15
22321 C02 8:00 pm - 8:50 pm T   Lewis Library   306   Enrolled:13 Limit:15
22322 C03 3:30 pm - 4:20 pm Th   McDonnell Hall   104   Enrolled:9 Limit:15
22323 C04 7:30 pm - 8:20 pm W   Lewis Library   306   Enrolled:14 Limit:15
22324 C05 7:30 pm - 8:20 pm W        Enrolled:0 Limit:0 Canceled