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An overview of several approaches to implementing quantum information and computation, touching briefly on quantum algorithms, but the main focus being physical systems. In particular, the course discusses what makes a good quantum system, the physics behind the leading implementations, and the limitations on each. Topics covered will include: superconducting qubits, electron and nuclear spin qubits, and ion trap qubits, as well as descriptions of gate-based, adiabatic, and topologically protected quantum architectures.