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Course Details

Spring 2010-2011
CHM 542   Graded A-F, P/D/F, Audit

Principles of Macromolecular Structure: Protein Folding, Structure and Design

Michael H. Hecht

This course will be taught from the scientific literature. We will begin the semester with several classic papers on protein folding. As the semester progresses, we will read about protein structure, stability, and folding pathways. The latter part of the semester will focus on recent papers describing new research aimed toward the construction of novel proteins from "scratch." These papers will cover topics ranging from evolution in vitro to computational and rational design. The course will end by discussing the possibility of creating artificial proteomes in the laboratory, and further steps toward synthetic biology.

Sample reading list:
Readings from current literature.,

Reading/Writing assignments:
Open to undergraduates only with permission of instructor.

Other Requirements:
Not Open to Freshmen.


Schedule/Classroom assignment:

Class numberSectionTimeDaysRoomEnrollmentStatus
40448 L01 01:30:00 pm - 02:50:00 pm M W   Jadwin Hall   A08   Enrolled:31 Limit:35
C01 01:30:00 pm - 02:20:00 pm Th   Lewis Library   134   Enrolled:0 Limit:15
C02 12:30:00 pm - 01:20:00 pm F   Lewis Library   117   Enrolled:0 Limit:15
C03 01:30:00 pm - 02:20:00 pm F   Lewis Library   117   Enrolled:0 Limit:15