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Course Details

Fall 2014-2015
* QCB 455 / MOL 455 / COS 455 (QR)   No Pass/D/Fail

Introduction to Genomics and Computational Molecular Biology

Anastasia Baryshnikova

The course will provide a detailed overview of experimental and computational approaches used to study molecular systesm. We will focus on modern technologies used to generate and alanlyze "omics" data, such as genome sequences, gene expression, transcriptional and post-transcriptional modification, proteomics and mass spectrometry, molecular interaction networks and chemical genomics. We will also discuss and apply fundamental statistical concepts relevant to genomics (data evaluation,estimation of true and false positives, significance testing, multiple testing correction) and learn basic programming tools.


Reading/Writing assignments:
In addition to regular homework exercises, students will be asked to design and carry out projects in groups of 3-4 students. Students will present their projects in an oral presentation and will describe their findings in a final paper formattedas a journal article.

Requirements/Grading:
Other Exam - 40%
Problem set(s) - 60%

Schedule/Classroom assignment:

Class numberSectionTimeDaysRoomEnrollmentStatus
21696 L01 11:00 am - 12:20 pm T Th   Carl C. Icahn Laboratory   101   Enrolled:16 Limit:30
21697 P01 7:30 pm - 8:20 pm W   Thomas Laboratory   222   Enrolled:15 Limit:30
23660 P02 7:30 pm - 8:20 pm Th   Thomas Laboratory   222   Enrolled:1 Limit:2