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Course Offerings

Course Evaluation Results

Course Details

Fall 2017-2018
* QCB 455 / MOL 455 / COS 455 (QR)   No Pass/D/Fail

Introduction to Genomics and Computational Molecular Biology

Joshua Akey
Michael S. Levine
Alejandro Ochoa
Mona Singh

The course will provide a detailed overview of experimental and computational approaches used to study molecular systems. We will focus on modern technologies used to generate and analyze "omics" data, such as genome sequences, gene expression, transcriptional and post-transcriptional modification, proteomics and mass spectrometry, molecular interaction networks and chemical genomics. We will also discuss and apply fundamental statistical concepts relevant to genomics (data evaluation,estimation of true and false positives, significance testing, multiple testing correction) and learn basic programming tools.

Reading/Writing assignments:
In addition to regular homework exercises, students will be asked to design and carry out projects in groups of 3-4 students. Students will present their projects in an oral presentation and will describe their findings in a final paper formatted as a journal article.

Other Exam - 40%
Problem set(s) - 60%

Prerequisites and Restrictions:
COS126 or equivalent preparation.

Schedule/Classroom assignment:

Class numberSectionTimeDaysRoomEnrollmentStatus
22192 L01 11:00:00 am - 12:20:00 pm T Th   Carl C. Icahn Laboratory   101   Enrolled:12 Limit:52