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Course Details

Spring 2011-2012
* EEB 414 / MOL 414   No Pass/D/Fail

Genetics of Human Populations

Peter Andolfatto
Leonid Kruglyak

This seminar will survey the evolutionary history of modern humans and the genetic basis of variation in our species through reading and discussion of classic and contemporary primary literature. Topics include the evolutionary origins of modern human populations, signatures of natural selection in the human genome, and approaches for discovering genetic variants that affect disease susceptibility and variation in normal traits. Significant emphasis will be placed on very recent advances made possible by the human genome project.

Sample reading list:
Knight, Julian C., Human Genetic Diversity: Functional Consequences for Health
Selected articles from scientific journals,
See instructor for complete list

Reading/Writing assignments:
Readings from the recent literature and problems to be handed out.

Take Home Final Exam - 40%
Class/Precept Participation - 30%
Problem set(s) - 30%

Prerequisites and Restrictions:
EEB 309, EEB 320, or MOL 342, or CHM 236/COS 236/MOL236/PHY236. Strong familiarity with genetics and molecular biology..

Schedule/Classroom assignment:

Class numberSectionTimeDaysRoomEnrollmentStatus
40792 S01 01:30:00 pm - 04:20:00 pm W   Carl C. Icahn Laboratory   280   Enrolled:17 Limit:24