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Course Details

Fall 2017-2018
CHM 440 / GHP 440   Graded A-F, P/D/F, Audit

Drug Discovery in the Genomics Era

Paul J. Reider

A detailed review of recent successes and failures in the discovery of new drugs. Therapeutic areas to be discussed include: HIV, oncology, asthma, Alzheimer's Disease, antibiotics, diabetes, and neglected diseases (malaria, TB, human African Trypaonosomiasis). Case studies presented by leading pharmaceutical scientists will complement discussions of the functional steps required to select a target, indentify a new chemical entity, and get it to patients. The course will emphasize the integration of the molecular sciences and the role of chemistry in inventing and producing important new medicines.


Sample reading list:
See instructor for complete list

Reading/Writing assignments:
Readings from the current literature.

Requirements/Grading:
Mid Term Exam - 35%
Final Exam - 35%
Papers - 15%
Class/Precept Participation - 15%

Other Requirements:
Open to Juniors, Seniors, and Graduate Students Only.

Prerequisites and Restrictions:
Two semesters of organic chemistry (CHM 301 & 302 OR CHM 303 & 304/304B) or the equivalent..

Reserved Seats:
GHP Certificate Students Only 15

Schedule/Classroom assignment:

Class numberSectionTimeDaysRoomEnrollmentStatus
20082 L01 3:00 pm - 4:20 pm M W        Enrolled:60 Limit:35 Closed
20083 C01 2:30 pm - 3:20 pm T        Enrolled:10 Limit:18
20084 C02 8:00 pm - 8:50 pm T        Enrolled:20 Limit:18 Closed
20085 C03 3:30 pm - 4:20 pm Th        Enrolled:22 Limit:20 Closed
20086 C04 7:30 pm - 8:20 pm W        Enrolled:8 Limit:18